Risk factors for Pseudomonas aeruginosa colonization in non-cystic fibrosis bronchiectasis and clinical implications

Abstract Background Pseudomonas aeruginosa is one of the commonest bacteria colonizing airway in patients with non-cystic fibrosis bronchiectasis. colonization associated poor outcomes bronchiectasis, including rapid decline lung function, exacerbation frequency and hospitalization. Methods A cross-sectional study Queen Mary Hospital, Hong Kong that included 350 Chinese bronchiectasis to investigate risk factors for clinical implications on disease outcomes. Discussions was more commonly found longer duration those proton pump inhibitors (PPIs) adjusted ORs 1.066 (95% CI = 1.036–1.096, p < 0.001) 2.815 1.307–6.064, 0.008) respectively. Patients have extensive involvement higher risks requiring hospitalization 2.445 1.283–4.657, 0.007) 2.745 1.012–7.449, 0.047) common among PPI.